Guardian

An individual who is authorized under applicable State or local law to consent on behalf of a child to general medical care. The role of a guardian in the context of research involving a child who is a ward is to provide permission, in lieu of a child’s biological or adoptive parents, for the ward to participate in the research. Common Rule, 2018 Requirements: 45 CFR 46.402, Subpart D, Definitions; FDA: 21 CFR 50.3, Definitions